Recent reviews

2023

Mahmoud O, Oladipo O, Mahmoud RH, Yosipovitch G. Itch: from the skin to the brain - peripheral and central neural sensitization in chronic itch. Front Mol Neurosci 2023:16:1272230. doi: 10.3389/fnmol.2023.1272230 https://www.frontiersin.org/articles/10.3389/fnmol.2023.1272230/full

2022

Tseng PY, Hoon MA. Interactions of the Neuro‒Immune‒Stromal Triad in Itch. J Invest Dermatol 2022; 142(1):42-46. doi: 10.1016/j.jid.2021.08.443
https://www.jidonline.org/article/S0022-202X(21)02340-X/fulltext

Sutaria N, Adawi W, Goldberg R, Roh YS, Choi J, Kwatra SG. Itch: Pathogenesis and treatment. J Am Acad Dermatol 2022; 86(1):17-34. doi: 10.1016/j.jaad.2021.07.078
https://www.jaad.org/article/S0190-9622(21)02635-9/fulltext

Roh YS, Choi J, Sutaria N, Kwatra SG. Itch: Epidemiology, clinical presentation, and diagnostic workup. J Am Acad Dermatol 2022; 86(1):1-14. doi: 10.1016/j.jaad.2021.07.076 https://www.jaad.org/article/S0190-9622(21)02369-0/fulltext

2021

Misery L, Brenaut E, Pierre O, Le Garrec R, Gouin O, Lebonvallet N, Abasq-Thomas C, Talagas M, Le Gall-Ianotto C, Besner-Morin C, Fluhr JW, Leven C. Chronic itch: emerging treatments following new research concepts. Br J Pharmacol 2021; 178(24):4775-4791. doi: 10.1111/bph.15672
https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15672

Lipman ZM, Yosipovitch G. Substance use disorders and chronic itch. J Am Acad Dermatol 2021; 84(1):148-155. doi: 10.1016/j.jaad.2020.08.117
https://www.jaad.org/article/S0190-9622(20)32545-7/fulltext

Erickson S, Heul AV, Kim BS. New and emerging treatments for inflammatory itch. Ann Allergy Asthma Immunol 2021; 126(1):13-20. doi: 10.1016/j.anai.2020.05.028 https://www.annallergy.org/article/S1081-1206(20)30391-4/fulltext

2020

Stefaniak AA, Białynicki-Birula R, Krajewski PK, Matusiak Ł, Goldust M, Szepietowski JC. tch in the era of COVID-19 pandemic: An unfolding scenario. Dermatol Ther 2020; 33(5):e13477. doi: 10.1111/dth.13477
https://onlinelibrary.wiley.com/doi/10.1111/dth.13477

Kremer AE, Mettang T, Weisshaar E. Non-dermatological Challenges of Chronic Itch. Acta Derm Venereol 2020; 100(2):adv00025. doi: 10.2340/00015555-3345
https://www.medicaljournals.se/acta/content/abstract/10.2340/00015555-3345

Fowler E, Yosipovitch G. A New Generation of Treatments for Itch. Acta Derm Venereol 2020; 100(2):adv00027. doi: 10.2340/00015555-3347
https://www.medicaljournals.se/acta/content/abstract/10.2340/00015555-3347

Chung BY, Um JY, Kim JC, Kang SY, Park CW, Kim HO. Pathophysiology and Treatment of Pruritus in Elderly. Int J Mol Sci 2020; 22(1):174. doi: 10.3390/ijms22010174
https://www.mdpi.com/1422-0067/22/1/174

Cevikbas F, Lerner EA. Physiology and Pathophysiology of Itch. Physiol Rev 2020; 100(3): 945-982. doi: 10.1152/physrev.00017.2019
https://journals.physiology.org/doi/full/10.1152/physrev.00017.2019?rfr_dat=cr_pub++0pubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org

2019

Yosipovitch G, Misery L, Proksch E, Metz M, Ständer S, Schmelz M. Skin Barrier Damage and Itch: Review of Mechanisms, Topical Management and Future Directions. Acta Derm Venereol 2019; 99(13):1201-1209. doi: 10.2340/00015555-3296
https://www.medicaljournals.se/acta/content/abstract/10.2340/00015555-3296

Kremer AE. What are new treatment concepts in systemic itch? Exp Dermatol 2019; 28(12):1485-1492. doi: 10.1111/exd.14024
https://onlinelibrary.wiley.com/doi/10.1111/exd.14024

Hashimoto T, Yosipovitch G. Itching as a systemic disease. J Allergy Clin Immunol 2019; 144(2):375-380. doi: 10.1016/j.jaci.2019.04.005
https://www.jacionline.org/article/S0091-6749(19)30521-4/fulltext

Hashimoto T, Rosen JD, Sanders KM, Yosipovitch G. Possible roles of basophils in chronic itch. Exp Dermatol 2019; 28(12):1373-1379. doi: 10.1111/exd.13705
https://onlinelibrary.wiley.com/doi/10.1111/exd.13705

2018

Zeidler C, Yosipovitch G, Ständer S (2018) Prurigo Nodularis and Its Management. Dermatol Clin 36(3):189-197. doi: 10.1016/j.det.2018.02.003
https://www.sciencedirect.com/science/article/abs/pii/S0733863518300147?via%3Dihub

Yosipovitch G, Rosen JD, Hashimoto T (2018) Itch: From mechanism to (novel) therapeutic approaches. J Allergy Clin Immunol 142(5):1375-1390. doi: 10.1016/j.jaci.2018.09.005
https://www.jacionline.org/article/S0091-6749(18)31352-6/fulltext
 
Sanders KM, Akiyama T (2018) The vicious cycle of itch and anxiety. Neurosci Biobehav Rev 87:17-26. doi: 10.1016/j.neubiorev.2018.01.009
https://www.sciencedirect.com/science/article/abs/pii/S0149763417305687?via%3Dihub

Rosen JD, Fostini AC, Yosipovitch G. Diagnosis and Management of Neuropathic Itch. Dermatol Clin 2018; 36(3):213-224. doi: 10.1016/j.det.2018.02.005
https://www.sciencedirect.com/science/article/abs/pii/S0733863518300160?via%3Dihub

Pavlis J, Yosipovitch G. Management of Itch in Atopic Dermatitis. Am J Clin Dermatol 2018; 19(3):319-332. doi: 10.1007/s40257-017-0335-4
https://link.springer.com/article/10.1007/s40257-017-0335-4

Misery L, Dutray S, Chastaing M, Schollhammer M, Consoli SG, Consoli SM. Psychogenic itch. Transl Psychiatry 2018; 8(1):52. doi: 10.1038/s41398-018-0097-7
https://www.nature.com/articles/s41398-018-0097-7

Lerner EA. Pathophysiology of Itch. Dermatol Clin 2018; 36(3):175-177. doi: 10.1016/j.det.2018.02.001
https://www.sciencedirect.com/science/article/abs/pii/S0733863518300123?via%3Dihub

Jannic A, Bernigaud C, Brenaut E, Chosidow O. Scabies Itch. Dermatol Clin 2018; 36(3):301-308. doi: 10.1016/j.det.2018.02.009
https://www.sciencedirect.com/science/article/abs/pii/S0733863518300202?via%3Dihub

Elmariah SB. Diagnostic Work-up of the Itchy Patient. Dermatol Clin 2018; 36(3):179-188. doi: 10.1016/j.det.2018.02.002
https://www.sciencedirect.com/science/article/abs/pii/S0733863518300135?via%3Dihub

Düll MM, Kremer AE. Management of Chronic Hepatic Itch. Dermatol Clin 2018; 36(3):293-300. doi: 10.1016/j.det.2018.02.008
https://www.sciencedirect.com/science/article/abs/pii/S0733863518300196?via%3Dihub

2017

Nowak DA, Yeung J. Diagnosis and treatment of pruritus. Can Fam Physician 2017; 63(12):918-924. https://www.cfp.ca/content/63/12/918.long

2006-2016

Şavk E. Neurologic Itch Management. Curr Probl Dermatol 2016; 50:116-23. doi: 10.1159/000446053
https://pubmed.ncbi.nlm.nih.gov/27578080/

Sun S, Dong X. Trp channels and itch. Semin Immunopathol. 2016;38(3):293-307.
http://link.springer.com/article/10.1007%2Fs00281-015-0530-4

Andersen HH, Arendt-Nielsen L, Gazerani P. Glial Cells are Involved in Itch Processing. Acta Derm Venereol. 2016 Feb 11.
http://www.medicaljournals.se/acta/content/?doi=10.2340/00015555-2366

Ji RR. Neuroimmune interactions in itch: Do chronic itch, chronic pain, and chronic cough share similar mechanisms? Pulm Pharmacol Ther. 2015;35:81-6.
http://www.sciencedirect.com/science/article/pii/S1094553915000954

Weisshaar E. Epidemiology of uraemic itch: New data. Eur J Pain. 2015 Sep 28.
http://onlinelibrary.wiley.com/doi/10.1002/ejp.761/abstract;jsessionid=E6F9213E46461ECDC7A57464592CDF13.f03t01

Pongcharoen P, Fleischer AB Jr. An evidence-based review of systemic treatments for itch. Eur J Pain. 2015 Sep 28.
http://onlinelibrary.wiley.com/doi/10.1002/ejp.766/abstract

Szepietowski JC, Reich A. Pruritus in psoriasis: An update. Eur J Pain. 2015 Sep 28.
http://onlinelibrary.wiley.com/doi/10.1002/ejp.768/abstract

Bartels DJ, van Laarhoven AI, van de Kerkhof PC, Evers AW. Placebo and nocebo effects on itch: effects, mechanisms, and predictors. Eur J Pain. 2015 Sep 28.
http://onlinelibrary.wiley.com/doi/10.1002/ejp.750/abstract

Schut C, Rädel A, Frey L, Gieler U, Kupfer J. Role of personality and expectations for itch and scratching induced by audiovisual itch stimuli. Eur J Pain. 2015 Sep 28.
http://onlinelibrary.wiley.com/doi/10.1002/ejp.751/abstract

Murota H, Katayama I. Evolving understanding on the aetiology of thermally provoked itch. Eur J Pain. 2015 Sep 28.
http://onlinelibrary.wiley.com/doi/10.1002/ejp.777/abstract

Rowe B, Yosipovitch G. Malignancy-associated pruritus. Eur J Pain. 2015 Sep 28.
http://onlinelibrary.wiley.com/doi/10.1002/ejp.760/abstract

Schut C, Grossman S, Gieler U, Kupfer J, Yosipovitch G. Contagious itch: what we know and what we would like to know. Front Hum Neurosci. 2015;9:57.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324061/

Mochizuki H, Kakigi R. Itch and brain. J Dermatol. 2015 Aug;42(8):761-7.
http://onlinelibrary.wiley.com/doi/10.1111/1346-8138.12956/abstract;jsessionid=92F6AF3DB4700B14DC572E4664E6A9E4.f04t04

Andersen HH, Elberling J, Arendt-Nielsen L. Human Surrogate Models of Histaminergic and Non-histaminergic Itch. Acta Derm Venereol. 2015 Oct 5;95(7):771-7.
http://www.medicaljournals.se/acta/content/?doi=10.2340/00015555-2146&html=1

Luo J, Feng J, Liu S, Walters ET, Hu H. Molecular and cellular mechanisms that initiate pain and itch. Cell Mol Life Sci. 2015;72(17):3201-23.
http://link.springer.com/article/10.1007%2Fs00018-015-1904-4

Mochizuki H, Kakigi R. Central mechanisms of itch. Clin Neurophysiol. 2015;126(9):1650-60.
http://www.sciencedirect.com/science/article/pii/S1388245714008116

Green D, Dong X. Supporting itch: a new role for astrocytes in chronic itch. Nat Med. 2015;21(8):841-2.
http://www.nature.com/nm/journal/v21/n8/full/nm.3921.html

Weisshaar E, Weiss M, Mettang T, Yosipovitch G, Zylicz Z. Paraneoplastic itch: an expert position statement from the Special Interest Group (SIG) of the International Forum on the Study of Itch (IFSI). Acta Derm Venereol. 2015;95(3):261-5.
http://www.medicaljournals.se/acta/content/?doi=10.2340/00015555-1959

Hoon MA. Molecular dissection of itch. Curr Opin Neurobiol. 2015;34:61-6.
http://www.sciencedirect.com/science/article/pii/S0959438815000264

van Laarhoven AI, van der Sman-Mauriks IM, Donders AR, Pronk MC, van de Kerkhof PC, Evers AW. Placebo effects on itch: a meta-analysis of clinical trials of patients with dermatological conditions. J Invest Dermatol. 2015;135(5):1234-43.
http://www.nature.com/jid/journal/v135/n5/full/jid2014522a.html

Braz J, Solorzano C, Wang X, Basbaum AI. Transmitting pain and itch messages: a contemporary view of the spinal cord circuits that generate gate control. Neuron. 2014;82(3):522-36.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492533/

Tominaga M, Takamori K. Itch and nerve fibers with special reference to atopic dermatitis: therapeutic implications. J Dermatol. 2014;41(3):205-12.
http://onlinelibrary.wiley.com/doi/10.1111/1346-8138.12317/abstract

Undem BJ, Taylor-Clark T. Mechanisms underlying the neuronal-based symptoms of allergy. J Allergy Clin Immunol. 2014;133(6):1521-34.
http://www.sciencedirect.com/science/article/pii/S0091674913018472

Dhand A, Aminoff MJ. The neurology of itch. Brain. 2014;137(Pt 2):313-22.
http://brain.oxfordjournals.org/content/137/2/313.long

Misery L, Brenaut E, Le Garrec R, Abasq C, Genestet S, Marcorelles P, Zagnoli F. Neuropathic pruritus. Nat Rev Neurol. 2014;10(7):408-16.
http://www.nature.com/nrneurol/journal/v10/n7/full/nrneurol.2014.99.html

Oaklander AL. Neuropathic Itch. In: Carstens E, Akiyama T, editors. Itch: Mechanisms and Treatment. Boca Raton (FL): CRC Press; 2014. Chapter 7.
http://www.ncbi.nlm.nih.gov/books/NBK200940/

Bautista DM, Wilson SR, Hoon MA. Why we scratch an itch: the molecules, cells and circuits of itch. Nat Neurosci. 2014;17(2):175-82.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364402/

Han L, Dong X. Itch mechanisms and circuits. Annu Rev Biophys. 2014;43:331-55.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081479/

LaMotte RH, Dong X, Ringkamp M. Sensory neurons and circuits mediating itch. Nat Rev Neurosci. 2014 Jan;15(1):19-31.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096293/

Kremer AE, Feramisco J, Reeh PW, Beuers U, Oude Elferink RP. Receptors, cells and circuits involved in pruritus of systemic disorders. Biochim Biophys Acta. 2014;1842(7):869-92.
http://www.sciencedirect.com/science/article/pii/S0925443914000465

Namer B, Reeh P. Scratching an itch. Nat Neurosci. 2013;16(2):117-8.
http://www.nature.com/neuro/journal/v16/n2/full/nn.3316.html

Akiyama T, Carstens E. Neural processing of itch. Neuroscience. 2013;250:697-714.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772667/

Yosipovitch G, Bernhard JD. Clinical practice. Chronic pruritus. N Engl J Med. 2013;368(17):1625-34.
http://www.nejm.org/doi/full/10.1056/NEJMcp1208814

Oaklander AL. Common neuropathic itch syndromes. Acta Derm Venereol. 2012;92(2):118-25.
http://www.medicaljournals.se/acta/content/?doi=10.2340/00015555-1318&html=1

Ross SE. Pain and itch: insights into the neural circuits of aversive somatosensation in health and disease. Curr Opin Neurobiol. 2011;21(6):880-7.
http://www.sciencedirect.com/science/article/pii/S0959438811001784

LaMotte RH, Shimada SG, Sikand P. Mouse models of acute, chemical itch and pain in humans. Exp Dermatol. 2011;20(10):778-82.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177101/

Jeffry J, Kim S, Chen ZF. Itch signaling in the nervous system. Physiology (Bethesda). 2011;26(4):286-92.
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Handwerker HO. Microneurography of pruritus. Neurosci Lett. 2010;470(3):193-6.
http://www.sciencedirect.com/science/article/pii/S0304394009008891

Schepers RJ, Ringkamp M. Thermoreceptors and thermosensitive afferents. Neurosci Biobehav Rev. 2010;34(2):177-84.
http://www.sciencedirect.com/science/article/pii/S0149763409001559

Davidson S, Giesler GJ. The multiple pathways for itch and their interactions with pain. Trends Neurosci. 2010;33(12):550-8.
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Schmelz M. Itch and pain. Neurosci Biobehav Rev. 2010;34(2):171-6.
http://www.sciencedirect.com/science/article/pii/S0149763408002066

Yosipovitch G, Carstens E, McGlone F. Chronic itch and chronic pain: Analogous mechanisms. Pain. 2007;131(1-2):4-7.
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Ständer S, Weisshaar E, Mettang T, Szepietowski JC, Carstens E, Ikoma A, Bergasa N, Gieler U, Misery L, Wallengren J, Darsow U, Streit M, Metze D, Luger TA, Greaves MW, Schmelz M, Yosipovitch G, Bernhard J. Clinical classification of itch: a position paper of the International Forum for the Study of Itch. Acta Derm Venereol 2007; 87:291-294.
http://www.medicaljournals.se/acta/content/?doi=10.2340/00015555-0305&html=1

Steinhoff M, Bienenstock J, Schmelz M, Maurer M, Wei E, Bíró T. Neurophysiological, neuroimmunological, and neuroendocrine basis of pruritus. J Invest Dermatol. 2006;126(8):1705-18.
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Ikoma A, Steinhoff M, Ständer S, Yosipovitch G, Schmelz M. The neurobiology of itch. Nat Rev Neurosci. 2006;7(7):535-47.
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Ständer S, Schmelz M. Chronic itch and pain--similarities and differences. Eur J Pain. 2006;10(5):473-8.
http://onlinelibrary.wiley.com/doi/10.1016/j.ejpain.2006.03.005/abstract

Paus R, Schmelz M, Bíró T, Steinhoff M. Frontiers in pruritus research: scratching the brain for more effective itch therapy. J Clin Invest. 2006;116(5):1174-86.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1451220/